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PRISM

Unit Presentation
The laboratory PRISM (Proteomic, Inflammatory Response, Mass Spectrometry), U1192 Inserm has been created as an Inserm Unit in 2015. The laboratory is organized as a single-team unit around two main axes, one devoted to Technological Innovations and the second to Therapeutic Innovations. This laboratory is associated to the Department of Surgery and Cancer of Imperial College London (ICL) as a European Associated Laboratory (EAL) recognized by Inserm and ICL. This EAL is named Lancet and has been created in 2017. In October 2017, PRISM has integrated a private company, Oncovet Clinical Research (www.oncovet-clinical-research.com/). A mixed private/public team has emerged as O’DREAMS (Oncological Driven associated Mass Spectrometry) team. O’DREAMS is financially supported by the Regional Council of Hauts-de-France and EU through a FEDER funding.
PRISM also includes a service platform, CLIC-Imaging, based on competences derived from basic science research of the lab. Most of the services are dedicated to demands from industry, although academics can also use the platform. Clic-imaging offers service in OMICS, Mass spectrometry imaging (MSI). 3D Cell OMICs offers service in organoids with 3D cell culture of mixed spheroids with immune cells or explants for drug efficiency tests; and exosome studies such as for development of therapeutic agents or for diagnosis.