Dr. Jacopo VIZIOLI

Associate Professor

Research member of the "Microglial Activation Axis" in the laboratory

Laboratoire PRISM - Unité Inserm 1192
Université de Lille - Campus Cité Scientifique
Faculté des Sciences et Technologies
Département de Biologie
Avenue Paul Langevin - Bâtiment SN3
59655 Villeneuve d'Ascq Cedex

Tel : +33 (0)3 20 43 68 39
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  • 1997: Ph.D. in Microbiology and Epidemiology - Rome 1 University, Italy
  • 1993: Graduated in Biology Scieces - Rome 1 University, Italy
  • 1987: Graduated in Natural Sciences - Rome 1 University, Italy

Research Activity

  • Investigation on microglia recruitment and inflammation control mechanisms in medicinal leech CNS. Characterization of inflammatory markers in leech Hirudo medicinalis nervous system and peripherical tissues
  • 18 publications
  • 10 proceedings
  • Member of the Editorial Board of Invertebrate Survival Journal (ISJ).

Professional Experience

Post-doctoral fellowship (1997-1999: funding Institute Pasteur-Cenci Bolognetti Fundation-Italy) and research member (1999-2001; CNRS contract) in insect immunity at the “Institut de Biologie Moléculaire et Cellulaire - IBMC“ (director Prof. Jules Hoffmann) Strasbourg, France.

Pedagogic Animation 

Animal Biology teacher (Lille 1 University). Organization of three units of the License “Life Sciences and Environment” (Lille 1 University). 
Development of multimedia tools for biology teaching; design and construction of didactical movies on animal anatomy.


Prize for the best lecture at the 1st pedagogic university movies festival (Lyon 2012, France)


  • Member of the Biology Department council 
  • Health & Safety laboratory correspondant

Principal Publications

Arafah K., Croix D., Vizioli J., Desmons A., Fournier I., Salzet M. (2013) Involvement of Nitric oxide through endocannabinoids release in microglia activation during the course of CNS regeneration in the medicinal leech. Glia 61:636-649. 
Tahtouh M, Croq F, Vizioli J, Garcon-Bocquet A, Sautiere PE, Van Camp C, Salzet M, Nagnan-Le Meillour P, Pestel J, Lefebvre C. (2012) HmC1q induces leech microglial cells chemotaxis via a binding to gC1qR homolog in Hirudo medicinalis. Journal of Neuroinflammation 9:37
Grimaldi A., Banfi S., Vizioli J., Tettamanti G., Noonan D. M., de Eguileor M. Cytokine Loaded Biopolymers as a Novel Strategy to Study Stem Cells during Wound Healing Processes. Macromol. Biosci. (2011) 11(8):1008-1019.
Croq F, Vizioli J, Tuzova M, Tahtouh M, Sautiere PE, Van Camp C, Salzet M, Cruikshank WW, Pestel J, Lefebvre C (2010) A homologous form of human interleukin 16 is implicated in microglia recruitment following nervous system injury in leech Hirudo medicinalis. Glia 58:1649-1662.
Tahtouh M, Croq F, Vizioli J, Sautiere PE, Van Camp C, Salzet M, Daha MR, Pestel J, Lefebvre C (2009) Evidence for a novel chemotactic C1q domain-containing factor in the leech nerve cord. Mol Immunol 46:523-531.
Vizioli, J. & Salzet, M. (2002) Antimicrobial peptides from animals: focus on invertebrates. Trends Pharm. Sci. 23 (11): 494-496.
Vizioli, J. & Salzet, M. (2002) Antimicrobial peptides versus parasitic infections? Trends Parasitol. 18: 475-476.
Vizioli, J., Bulet, P., Hoffmann, J.A., Kafatos, F.C., Müller, H.M., and Dimopoulos, G. (2001) Gambicin: a novel immune responsive antimicrobial peptide from the malaria vector Anopheles gambiae. Proc. Natl. Acad. Sci. U.S.A. 98 (22): 12630-12635.
Vizioli, J., Bulet, P., Charlet, M., Lowenberger, C., Blass, C., Müller, H.M., Dimopoulos, G., Hoffmann, J., Kafatos, F.C., Richman, A. (2000) Cloning and analysis of a cecropin gene from the malaria vector mosquito, Anopheles gambiae. Insect Mol. Biol. 9 (1): 75-84.