The MS4Omics platform of the PRISM Inserm U1192 laboratory offers expertise in proteomics and mass spectrometry imaging (MSI).
In proteomics, it specialises in non-targeted approaches (bottom-up, shotgun and top-down) and interactomics (cross-linking MS and BioID). Particular expertise has been acquired in tissue analysis using spatial proteomics, FFPE tissue analysis, proteogenomics and the purification, quantification and analysis of exosomes. The link between the platform and the laboratory enables the platform to offer unique expertise.
MS4Omics takes on requests from local, regional and national academics and industry, or from outside France.
- TimsTOF-Flex, Bruker
- High-throughput MALDI MS Imaging: MALDI-TOF, RapiFlex Tissue typer, Bruker
- In vivo and ex vivo MS by SpiderMass: ESI/REIMS-QTOF Xevo G2-XS, Waters
- Imagerie DESI MS :ESI/DESI-QTOF with ion mobility separation and ETD fragmentation,SYNAPT G2S, Waters
- Large-scale proteomics: LC-MS: NanoUHPLC Acquity nanoESI/QObitrap with HCD fragmentation QExactive, Thermo Fisher Scientific
nLC, Evosep One, EVOSEP ESI-Q-orbitrap QExactive,Thermo Fisher Scientific - Métabolomique & Top Down proteomics: Shimadzu UFLC HESI-Orbitrap VELOS ELITE HCD/CID
- Software: MaxQuant, ProteomeDiscoverer (V2.5), SCILS, Progenesis